Bacterial resistance to fluoroquinolones.

doi:10.1093/clinids/10.supplement_1.s57

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Article

Bacterial resistance to fluoroquinolones.

Reviews of infectious diseases - 1 Jan 2000

Neu H C

Abstract excerpt

Fluoroquinolones inhibit bacteria by interacting with the A subunit of DNA gyrase. Resistance to older agents such as nalidixic acid was due to mutations in the gyrA gene. Resistance to the new fluoroquinolones (e.g., norfloxacin, enoxacin, ofloxacin, pefloxacin, and ciprofloxacin) as a consequen...

Topics

Anti-Bacterial Agents
Bacteria
Drug Resistance, Microbial
Fluorine
Humans
Mutation
Quinolines

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