Article
Bacterial resistance to fluoroquinolones: lessons to be learned.
Infection - 1 Jan 1994
Ball P
Abstract excerpt
Resistance to fluoroquinolone antibacterials has emerged in a limited form, largely amongst certain specific species and often restricted to single clones of these pathogens. Mediated by chromosomal mutation, the major mechanisms are alterations in gyrase subunits and reduced penetration associat...
Topics
- Anti-Infective Agents
- Bacterial Infections
- Cross Infection
- DNA Topoisomerases, Type II
- DNA, Bacterial
- Disease Transmission, Infectious
- Drug Resistance, Microbial
- Drug Utilization
- Fluoroquinolones
- Humans
- Infection Control
- Microbial Sensitivity Tests