Article
Bacterial resistance to fluoroquinolones: lessons to be learned.
Infection - 1 Jan 1994
Ball P
Abstract excerpt
Resistance to fluoroquinolone antibacterials has emerged in a limited form, largely amongst certain specific species and often restricted to single clones of these pathogens. Mediated by chromosomal mutation, the major mechanisms are alterations in gyrase subunits and reduced penetration associated with decreased outer membrane protein production. Resistance is most commonly seen to emerge amongst pathogens with...
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