Article
A Self-Priming Digital Polymerase Chain Reaction Chip for Multiplex Genetic Analysis.
ACS nano - 25 Aug 2020
Yin Juxin, Zou Zheyu, Yin Fangfang, Liang Hongxiao, Hu Zhenming, Fang Weibo, Lv Shaowu, Zhang Tao, Wang Ben, Mu Ying
Abstract excerpt
Digital PCR (polymerase chain reaction) is a powerful and attractive tool for the quantification of nucleic acids. However, the multiplex detection capabilities of this system are limited or require expensive instrumentation and reagents, all of which can hinder multiplex detection goals. Here, we propose strategies toward solving these issues regarding digital PCR. We designed and tested a self-priming digital...
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