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Article

A direct and multiplex digital PCR chip for EGFR mutation.

Talanta - 1 Dec 2022

Yin Juxin, Xia Liping, Zou Zheyu, Zhuang Jianjian, Mu Ying

Abstract excerpt

Digital PCR is a sensitive detection method, which has important applicability in liquid biopsy through the measurement of ctDNA. However, the current sample pre-processing of ctDNA and the multiplex detection capability of digital PCR have limitations. In view of the above two aspects, we developed a digital PCR chip with multiplex capability and established a direct amplification detection method without...

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PMID: 35834974
DOI: 10.1016/j.talanta.2022.123725

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