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Article

Analysis of rare variants of autosomal-dominant genes in a Chinese population with sporadic Parkinson's disease.

Molecular genetics & genomic medicine - 1 Oct 2020

Zheng Ran, Jin Chong-Yao, Chen Ying, Ruan Yang, Gao Ting, Lin Zhi-Hao, Dong Jia-Xian, Yan Ya-Ping, Tian Jun, Pu Jia-Li, Zhang Bao-Rong

Abstract excerpt

BACKGROUND: To date, several studies have suggested that genes involved in monogenic forms of Parkinson's disease (PD) contribute to unrelated sporadic cases, but there is limited evidence in the Chinese population. METHODS: We performed a systematic analysis of 12 autosomal-dominant PD (AD-PD) genes (SNCA, LRRK2, GIGYF2, VPS35, EIF4G1, DNAJC13, CHCHD2, HTRA2, NR4A2, RIC3, TMEM230, and UCHL1) using panel...

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Source

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Identifiers

PMID: 32794657
DOI: 10.1002/mgg3.1449
PMCID: PMC7549569

Genes

CHCHD2
DNAJC13
EIF4G1
GIGYF2
HTRA2
NR4A2
RIC3
SNCA
TMEM230
UCHL1
VPS35

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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