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Article

Interaction between a haptoglobin genetic variant and coronary artery disease (CAD) risk factors on CAD severity in Singaporean Chinese population.

Molecular genetics & genomic medicine - 1 Oct 2020

Chang Xuling, Dorajoo Rajkumar, Han Yi, Wang Ling, Liu Jianjun, Khor Chiea-Chuen, Low Adrian F, Chan Mark Yan-Yee, Yuan Jian-Min, Koh Woon-Puay, Friedlander Yechiel, Heng Chew-Kiat

Abstract excerpt

BACKGROUND: Haptoglobin (Hp) is a plasma protein with strong anti-inflammation and antioxidant activities. Its plasma level is known to be inversely associated with many inflammatory diseases, including cardiovascular diseases. However, the association of HP genetic variants with coronary artery disease (CAD) severity/mortality, and how they interact with common CAD risk factors are largely unknown. METHODS: We...

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Identifiers

PMID: 32794371
DOI: 10.1002/mgg3.1450
PMCID: PMC7549588

Genes

CAD
HP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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