Article
Application of a multiplex SNP genotyping system in predicting genetic susceptibility to CAD in Chinese people of Han ethnicity.
Medical science monitor : international medical journal of experimental and clinical research - 1 Dec 2010
Zhang Yangdong, Tian Yaping, Dong Jin, Li Liqing, Dong Zhennan, Deng Xinxin
Abstract excerpt
BACKGROUND: Coronary artery disease (CAD) is a multifactorial disease influenced by various genetic factors involved in accumulation of atherosclerosis in the walls of the coronary arteries. Many single nucleotide polymorphisms (SNPs) are associated with CAD. MATERIAL/METHODS: DNA samples were extracted from peripheral white blood cells and 32 tag SNPs of 12 genes (ADD1, PECAM-1, CRP, ecNOS, PC-1, SELL, GNB3,...
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