Article
C3 Gene Functional Polymorphisms and C3 Serum Levels in Patients with Rheumatoid Arthritis.
Immunological investigations - 1 Nov 2021
Sena Leia, Oliveira-Toré Camila F, Skare Thelma, de Messias-Reason Iara Jose, Andrade Fabiana Antunes
Abstract excerpt
The complement system is a key component of the innate immunity that plays a significant role in the development and clinical presentation of Rheumatoid arthritis (RA). Complement protein C3 is a central molecule in the activation of complement with a significant role in the inflammatory processes of RA. Nevertheless, the impact of C3 gene polymorphisms in the development of RA is still unknown. The current study...
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