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Article

Association of Three Functional Polymorphisms in the NLRP3 Gene with Susceptibility to Rheumatoid Arthritis in the Iranian Population.

Iranian journal of immunology : IJI - 1 Sept 2021

Nasrollahzadeh Sabet Mehrdad, Nasrabadi Navid, Jalili Zahra, Pakzad Bahram, Davar Saeideh, Ehtesham Naeim, Jafarpour Sima, Mosallaei Meysam, Esmaeilzadeh Emran

Abstract excerpt

BACKGROUND: Rheumatoid arthritis (RA) is a complex systemic autoimmune disorder with multifactorial nature. Numerous previous studies have shown that several genes are involved in the pathogenesis and increased risk of RA. The Nod-like receptor pyrin domain containing 3 (NLRP3) is involved in the regulation of innate immunity and its upregulation has previously been reported in RA. OBJECTIVE: To evaluate the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34596590
DOI: 10.22034/iji.2021.89507.1950

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