Article
Association of FCRL3 genotypes with susceptibility of Iranian patients to rheumatoid arthritis.
Immunological investigations - 1 Jan 2013
Golmoghaddam Hossein, Amirghofran Zahra, Aflaki Elham, Kamali-Sarvestani Eskandar, Shabani Mahdi, Esmaeilbeig Maryam, Rajabi Mona
Abstract excerpt
Rheumatoid arthritis (RA) is a complex disease, the hallmark of which is synovial joint inflammation. The substantial contribution from genetic factors in susceptibility to RA has been well-defined. The Fc receptor-like3 (FCRL3) gene is one of the genes that have recently shown a significant association with RA. To determine the possible role of FCRL3-169 C/T and FCRL3-110 A/G gene polymorphisms in the...
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