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Article

Effects of BAFF Neutralization on Atherosclerosis Associated With Systemic Lupus Erythematosus.

Arthritis & rheumatology (Hoboken, N.J.) - 1 Feb 2021

Saidoune Fanny, Even Guillaume, Lamri Yasmine, Chezel Julie, Gaston Anh-Thu, Escoubet Brigitte, Papo Thomas, Charles Nicolas, Nicoletti Antonino, Sacre Karim

Abstract excerpt

OBJECTIVE: Cardiovascular disease (CVD) is the leading cause of death in systemic lupus erythematosus (SLE). B cells play a key role in the pathogenesis of lupus, and anti-BAFF therapy has been approved for use in SLE. Since mature B cells also promote atherosclerosis, we undertook this study to evaluate, in a mouse model and in SLE patients, whether BAFF neutralization has an atheroprotective effect in SLE....

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PMID: 32783382
DOI: 10.1002/art.41485

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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