Article
Mycophenolate mofetil but not atorvastatin attenuates atherosclerosis in lupus-prone LDLr(-/-) mice.
Annals of the rheumatic diseases - 1 Mar 2012
van Leuven Sander I, Mendez-Fernandez Yanice V, Wilhelm Ashley J, Wade Nekeithia S, Gabriel Curtis L, Kastelein John J, Stroes Erik S, Tak Paul P, Major Amy S
Abstract excerpt
RATIONALE: Recent clinical and preclinical studies have demonstrated that systemic lupus erythematosus (SLE) is associated with an increased risk for cardiovascular disease (CVD). However, unlike in the general population, little is known regarding the efficacy of atheroprotective interventions in patients with SLE. The current study aims to determine the benefit of lymphocyte inhibition on reducing the...
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