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Genetics of Oocyte Maturation Defects and Early Embryo Development Arrest

22 Oct 2022

Abstract excerpt

Various pathogenic factors can lead to oogenesis failure and seriously affect both female reproductive health and fertility. Genetic factors play an important role in folliculogenesis and oocyte maturation but still need to be clarified. Oocyte maturation is a well-organized complex process, regulated by a large number of genes. Pathogenic variants in these genes as well as aneuploidy, defects in mitochondrial...

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PMID: 36360157
DOI: 10.3390/genes13111920

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