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Generation of induced pluripotent stem cell line (RCMGi001-A) from human skin fibroblasts of a cystic fibrosis patient with p.F508del mutation.

Stem cell research - 1 Oct 2020

Kondrateva Ekaterina, Adilgereeva Elmira, Amelina Elena, Tabakov Vyacheslav, Demchenko Anna, Ustinov Kirill, Yasinovsky Matvey, Voronina Ekaterina, Lavrov Alexander, Smirnikhina Svetlana

Abstract excerpt

Skin fibroblasts obtained from a 27-year-old man with clinically manifested and genetically proven (F508del/F508del) cystic fibrosis were successfully transformed into induced pluripotent stem cells (iPSCs) by using Sendai virus-based reprogramming vectors including the four Yamanaka factors, OCT3/4, SOX2, KLF4, and c-MYC. The iPSCs showed a normal karyotype, expressed pluripotency markers and exhibited the...

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Source

Identifiers

PMID: 32777768
DOI: 10.1016/j.scr.2020.101933

Genes

KLF4
MYC
SOX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Generation of induced pluripotent stem cell line (RCMGi001-A) from human skin fibroblasts of a cystic fibrosis patient with p.F508del mutation.PMID 32777768Read ↗

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