Article
Establishment of induced pluripotent stem cell line CSUASOi004-A by reprogramming peripheral blood mononuclear cells of a PRPF6-related dominant retinitis pigmentosa patient.
Stem cell research - 1 May 2020
Zhou Yalan, Jing Yutong, Mao Shengru, Liu Jian, Cui Zekai, Wang Yini, Chen Juan, Chan Hon Fai, Tang Shibo, Chen Jiansu
Abstract excerpt
We have established the patient-specific induced pluripotent stem (iPS) cell line CSUASOi004-A by using peripheral blood mononuclear cells (PBMCs) of a retinitis pigmentosa (RP) patient with a PRPF6 gene mutation (c.G2699A:p.R900H). CSUASOi004-A was established by a non-integrative method with four episomal plasmids containing the Yamanaka factors. The cell line with the specific point mutation had the typical...
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