Article
Cocaine-Induced Sensitization is Linked to Distal Chromosome 6 Region in Congenic Mouse Model.
Drug and alcohol dependence - 1 Oct 2020
Vadasz Csaba, Gyetvai Beatrix M
Abstract excerpt
OBJECTIVE: Previously we mapped QTL Eac2 to mouse Chr6 and identified the first gene (Grm7) as accounting for alcohol consumption in a mammalian model. Despite the central role of glutamate receptors in addiction, the effects of Grm7 gene variants are not well known. Here we test the hypothesis that genetic variation of the distal mouse Chr6 Eac2 region, location of Grm7, controls cocaine-induced locomotor...
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