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Article

UEP: an open-source and fast classifier for predicting the impact of mutations in protein-protein complexes.

Bioinformatics (Oxford, England) - 20 Apr 2021

Amengual-Rigo Pep, Fernández-Recio Juan, Guallar Victor

Abstract excerpt

MOTIVATION: Single protein residue mutations may reshape the binding affinity of protein-protein interactions. Therefore, predicting its effects is of great interest in biotechnology and biomedicine. Unfortunately, the availability of experimental data on binding affinity changes upon mutation is limited, which hampers the development of new and more precise algorithms. Here, we propose UEP, a classifier for...

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PMID: 32761082
DOI: 10.1093/bioinformatics/btaa708

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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