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Mutations in gyrB play an important role in ciprofloxacin-resistant Pseudomonas aeruginosa

1 Feb 2019

Abstract excerpt

Purpose: To investigate the main molecular resistance mechanisms to fluoroquinolones (FQs) in Pseudomonas aeruginosa and also to investigate the effect of time and concentration on mutations in resistance genes. Materials and methods: The clinical isolates of P. aeruginosa which are sensitive to ciprofloxacin (CIP) or levofloxacin (LEV) were collected. The isolates were incubated with different concentrations of...

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PMID: 30804676
DOI: 10.2147/idr.s182272

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