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MCF7 Spheroid Development: New Insight about Spatio/Temporal Arrangements of TNTs, Amyloid Fibrils, Cell Connections, and Cellular Bridges.

International journal of molecular sciences - 29 Jul 2020

Pulze Laura, Congiu Terenzio, Brevini Tiziana A L, Grimaldi Annalisa, Tettamanti Gianluca, D'Antona Paola, Baranzini Nicolò, Acquati Francesco, Ferraro Federico, de Eguileor Magda

Abstract excerpt

Human breast adenocarcinoma cells (MCF7) grow in three-dimensional culture as spheroids that represent the structural complexity of avascular tumors. Therefore, spheroids offer a powerful tool for studying cancer development, aggressiveness, and drug resistance. Notwithstanding the large amount of data regarding the formation of MCF7 spheroids, a detailed description of the morpho-functional changes during their...

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Identifiers

PMID: 32751344
DOI: 10.3390/ijms21155400
PMCID: PMC7432950

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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