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Breast Cancer MCF-7 Cell Spheroid Culture for Drug Discovery and Development

1 Jan 2022

Abstract excerpt

In vitro 3D cancer spheroids (tumoroids) exhibit a drug resistance profile similar to that found in solid tumors. 3D spheroid culture methods recreate more physiologically relevant microenvironments for cells. Therefore, these models are more appropriate for cancer drug screening. We have recently developed a protocol for MCF-7 cell spheroid culture, and used this method to test the effects of different types of...

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PMID: 36311820
DOI: 10.4236/jct.2022.133009

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