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MCF-7 Cells as a Three-Dimensional Model for the Study of Human Breast Cancer

1 Sept 2011

Abstract excerpt

The increasing use of three-dimensional (3D) cell culture is because it reproduces in vitro results similar to in vivo results. Multicellular tumor spheroids generated in vitro exhibit important characteristics of avascular tumors, mainly with respect to tumor physiology and microenvironment. The interaction among cells in a tridimensional culture environment enhances cell differentiation and leads to luminal...

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PMID: 21882900
DOI: 10.1089/ten.tec.2011.0260

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