Article

Nanoprotrusion enlargement conducts cytocapsular tube elongation along the path of least resistance for metastasis initiation

2025-02-13

Abstract excerpt

Cancer metastasis is a major source of cancer lethality. Recently, we reported that the ATP-dependent calcium pump PMCA2 is enriched in cytocapsular membranes as biomarker of native malignant tumors. Cytocapsular tubes (CCTs) provide membrane-enclosed freeways for protected and bi-directional cancer metastasis in cytocapsular tumor network systems (CTNSs). It is obscure how CCTs initiate and elongate in heterogene...

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Literature Corpus work: 496722a6-746c-5635-a30c-392722cb5487
DOI: 10.1101/2025.02.10.637526

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