[Genetics of osteoporosis].

Abstract excerpt

Osteoporosis is characterized by low bone mineral density (BMD) and microarchitectural deterioration of bone tissue, with a consequent increase in the fragility of bones and susceptibility to fractures. Over the last five years, genome-wide association studies (GWAS) have identified the single-nucleotide polymorphisms(SNPs) associated with osteoporosis, BMD and other determinants of fracture risk. These SNPs were...

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