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Article

GABRA2 rs279858-linked variants are associated with disrupted structural connectome of reward circuits in heroin abusers.

Translational psychiatry - 30 Jul 2018

Sun Yan, Zhang Yang, Zhang Dai, Chang Suhua, Jing Rixing, Yue Weihua, Lu Lin, Chen Dong, Sun Yankun, Fan Yong, Shi Jie

Abstract excerpt

The reward system plays a vital role in drug addiction. The purpose of this study is to investigate the structural connectivity characteristics and driving-control subnetwork patterns of reward circuits in heroin abusers and assess the genetic modulation on the reward network. We first defined the reward network based on systematic literature review, and built the reward network based on diffusion tensor imaging...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30061709
DOI: 10.1038/s41398-018-0180-0
PMCID: PMC6066482

Genes

GABRA2

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