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Article

Prognostic significance of serial molecular annotation in myelodysplastic syndromes (MDS) and secondary acute myeloid leukemia (sAML).

Leukemia - 1 Apr 2021

Yun Seongseok, Geyer Susan M, Komrokji Rami S, Al Ali Najla H, Song Jinming, Hussaini Mohammad, Sweet Kendra L, Lancet Jeffrey E, List Alan F, Padron Eric, Sallman David A

Abstract excerpt

The implementation of next-generation sequencing (NGS) has influenced diagnostic, prognostic, and therapeutic decisions in myeloid malignancies. However, the clinical relevance of serial molecular annotation in patients with myelodysplastic syndrome (MDS) undergoing active treatment is unknown. MDS or secondary acute myeloid leukemia (sAML) patients who had at least two NGS assessments were identified. Outcomes...

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Identifiers

PMID: 32728186
DOI: 10.1038/s41375-020-0997-4
PMCID: PMC7854836

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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