Article
Genetic Polymorphism of Epidermal Growth Factor Gene as a Predictor of Hepatocellular Carcinoma in Hepatitis C Cirrhotic Patients.
Asian Pacific journal of cancer prevention : APJCP - 1 Jul 2020
Baghdadi Ibrahim, Abu Ella Khaled, El Shaaraway Ahmed, Elshayeb Elsayed, El-Rebey Hala S, El Hoseeny Mohamed, Naguib Mary, Nada Ali
Abstract excerpt
BACKGROUND: In Egypt, the incidence of hepatocellular carcinoma (HCC) is approximately 4.7% of chronic liver disease patients due to (HCV) infection. Epidermal growth factor (EGF) plays an important role in hepatocyte regeneration. A functional polymorphism in EGF 61A>G was identified; itwas associated with higher risk of HCC. OBJECTIVES: to investigate the correlation between the epidermal growth factor (EGF)...
Topics
- Adult
- Aged
- Carcinoma, Hepatocellular
- Case-Control Studies
- ErbB Receptors
- Female
- Follow-Up Studies
- Genetic Predisposition to Disease
- Genotype
- Hepacivirus
- Hepatitis C
- Humans
- Liver Cirrhosis