Article
Association between epidermal growth factor 61A/G polymorphism and hepatocellular carcinoma susceptibility in Chinese patients.
Liver international : official journal of the International Association for the Study of the Liver - 1 Jan 2010
Li Yajuan, Xie Qing, Lu Fengmin, Zhao Jingmin, Mao Panyong, Li Zhuo, Liu Shuang, Zhuang Hui
Abstract excerpt
BACKGROUND AND AIMS: Chronic hepatitis B virus (HBV) infection is an important risk factor for hepatocellular carcinoma (HCC) development in China, while little is known of the genetic susceptibility to hepatocarcinogenesis. The epidermal growth factor (EGF) pathway plays an important role in tumorigenesis, including HCC. EGF polymorphisms are associated with susceptibility to several types of cancers. Therefore,...
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