Epidermal growth factor gene polymorphism and risk of hepatocellular carcinoma: a meta-analysis.

doi:10.1371/journal.pone.0032159

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Article

Epidermal growth factor gene polymorphism and risk of hepatocellular carcinoma: a meta-analysis.

PloS one - 1 Jan 2012

Zhong Jian-Hong, You Xue-Mei, Gong Wen-Feng, Ma Liang, Zhang Yu, Mo Qin-Guo, Wu Liu-Cheng, Xiao Jun, Li Le-Qun

Abstract excerpt

BACKGROUND: Hepatocarcinogenesis is a complex process that may be influenced by many factors, including polymorphism in the epidermal growth factor (EGF) gene. Previous work suggests an association between the EGF 61*A/G polymorphism (rs4444903) and susceptibility to hepatocellular carcinoma (HCC), but the results have been inconsistent. Therefore, we performed a meta-analysis of several studies covering a large...

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PMID: 22403631
DOI: 10.1371/journal.pone.0032159
PMCID: PMC3293888

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