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Article

NOTCH-1 Gene Mutations Influence Survival in Acute Myeloid Leukemia Patients.

Asian Pacific journal of cancer prevention : APJCP - 1 Jul 2020

Aref Salah, Rizk Rasha, El Agder Mohamed, Fakhry Wafaa, El Zafarany Maha, Sabry Mohamed

Abstract excerpt

BACKGROUND: Although NOTCH-1 gene mutations were reported to contributes to leukemogenesis in lymphocytic leukemias, its role in acute myeloid leukemia (AML) remains unclear. Therefor; this study was designed to determine the prevalence and clinical impact of NOTCH-1 mutations in AML patients. MATERIALS AND METHODS: In the current study, NOTCH-1 gene mutations were identified in Bone Marrow samples obtained from...

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Identifiers

PMID: 32711424
DOI: 10.31557/APJCP.2020.21.7.1987
PMCID: PMC7573420

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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