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Article

Landscape and clinical impact of NOTCH mutations in newly diagnosed acute myeloid leukemia.

Cancer - 15 Jan 2023

Han Haohao, Yao Yifang, Wang Hong, Zhou Meng, Zhang Ziyan, Xu Xiaoyan, Qi Jiaqian, Liu Yuejun, Wu Depei, Han Yue

Abstract excerpt

BACKGROUND: NOTCH mutations (NOTCHmut ) are recognized as major oncogenic drivers associated with controversial clinical impact on T-cell acute lymphoblastic leukemia (T-ALL), whereas their clinical value on acute myeloid leukemia (AML) is poorly defined. METHODS: A study involving 878 consecutive newly diagnosed patients with AML was undertaken in an institution with available clinical data to unravel the impact...

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Identifiers

PMID: 36370049
DOI: 10.1002/cncr.34534

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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