δ-Aminolevulinic acid dehydratase single nucleotide polymorphism 2 (ALAD2) and peptide transporter 2*2 haplotype (hPEPT2*2) differently influence neurobehavior in low-level lead exposed children.

doi:10.1016/j.ntt.2014.12.001

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Article

δ-Aminolevulinic acid dehydratase single nucleotide polymorphism 2 (ALAD2) and peptide transporter 22 haplotype (hPEPT22) differently influence neurobehavior in low-level lead exposed children.

Neurotoxicology and teratology - 1 Jan 2000

Sobin Christina, Flores-Montoya Mayra Gisel, Gutierrez Marisela, Parisi Natali, Schaub Tanner

Abstract excerpt

Delta-aminolevulinic acid dehydratase single nucleotide polymorphism 2 (ALAD2) and peptide transporter haplotype 2*2 (hPEPT2*2) through different pathways can increase brain levels of delta-aminolevulinic acid and are associated with higher blood lead burden in young children. Past child and adult findings regarding ALAD2 and neurobehavior have been inconsistent, and the possible association of hPEPT2*2 and...

Topics

Attention
Child
Child, Preschool
Choice Behavior
Developmental Disabilities
Female
Genetic Predisposition to Disease
Haplotypes
Humans
Lead
Male
Memory, Short-Term
Motor Activity

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neuropsychological Tests

Polymorphism, Single Nucleotide

Porphobilinogen Synthase

Symporters

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Identifiers

PMID: 25514583
DOI: 10.1016/j.ntt.2014.12.001
PMCID: PMC4291309

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