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Article

Increased mitochondrial respiration of adipocytes from metabolically unhealthy obese compared to healthy obese individuals.

Scientific reports - 24 Jul 2020

Böhm Anja, Keuper Michaela, Meile Tobias, Zdichavsky Marty, Fritsche Andreas, Häring Hans-Ulrich, de Angelis Martin Hrabě, Staiger Harald, Franko Andras

Abstract excerpt

Among obese subjects, metabolically healthy (MHO) and unhealthy obese (MUHO) subjects exist, the latter being characterized by whole-body insulin resistance, hepatic steatosis, and subclinical inflammation. Insulin resistance and obesity are known to associate with alterations in mitochondrial density, morphology, and function. Therefore, we assessed mitochondrial function in human subcutaneous preadipocytes as...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32709986
DOI: 10.1038/s41598-020-69016-9
PMCID: PMC7382448

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