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Article

Increased inflammation, oxidative stress and mitochondrial respiration in brown adipose tissue from obese mice.

Scientific reports - 22 Nov 2017

Alcalá Martín, Calderon-Dominguez María, Bustos Eduviges, Ramos Pilar, Casals Núria, Serra Dolors, Viana Marta, Herrero Laura

Abstract excerpt

Obesity is associated with severe metabolic diseases such as type 2 diabetes, insulin resistance, cardiovascular disease and some forms of cancer. The pathophysiology of obesity-induced metabolic diseases has been strongly related to white adipose tissue (WAT) dysfunction through several mechanisms such as fibrosis, apoptosis, inflammation, ER and oxidative stress. However, little is known of whether these...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29167565
DOI: 10.1038/s41598-017-16463-6
PMCID: PMC5700117

Genes

UCP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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