Article

Decreased Mitochondrial Bioenergetics and Function Define a Distinct Metabolic Phenotype in Healthy Sedentary Individuals Detectable Through Non-Invasive CPET

2024-08-19

Abstract excerpt

<h4>Background</h4> Physical inactivity is a major contributor to cardiometabolic disease and mortality. Although mitochondrial dysfunction characterizes overt pathology, whether a distinct mitochondrial phenotype is present in apparently healthy sedentary adults remains unclear. <h4>Methods</h4> Nine sedentary (SED) and ten physically active (AC) healthy males (42 ± 14 yr) were studied. Skeletal muscle bioenerg...

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Literature Corpus work: b80724de-5b0b-5b7c-9563-8d3bcba4e516
DOI: 10.1101/2024.08.19.608601

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