Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Role of BMI1 in Late-Onset Sporadic Alzheimer's Disease.

Genes - 21 Jul 2020

Hogan Ryan, Flamier Anthony, Nardini Eleonora, Bernier Gilbert

Abstract excerpt

Late-onset sporadic Alzheimer's disease (LOAD) seems to contain a "hidden" component that cannot be explained by classical Mendelian genetics, with advanced aging being the strongest risk factor. More surprisingly, whole genome sequencing analyses of early-onset sporadic Alzheimer's disease cohorts also revealed that most patients do not present classical disease-associated variants or mutations. In this short...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Epigenesis, Genetic
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polycomb Repressive Complex 1

Source

Open in PubMed Open full text

Identifiers

PMID: 32708145
DOI: 10.3390/genes11070825
PMCID: PMC7397074

Genes

BMI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Role of BMI1 in Late-Onset Sporadic Alzheimer's Disease.PMID 32708145Read ↗

Modeling Late-Onset Sporadic Alzheimer’s Disease through BMI1 DeficiencySemantic proximity Read ↗

<i>In vivo</i> validation of late-onset Alzheimer’s disease genetic risk factorsSemantic proximity Read ↗

Age-Specific Epigenetic Drift in Late-Onset Alzheimer's DiseaseSemantic proximity Read ↗

Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS).Semantic proximity Read ↗

The Bridging Integrator 1 Gene Polymorphism rs744373 and the Risk of Alzheimer's Disease in Caucasian and Asian Populations: An Updated Meta-Analysis.Semantic proximity Read ↗

Genetic variation in BIN1 gene and Alzheimer's disease risk in Han Chinese individuals.Semantic proximity Read ↗

Do epigenetic pathways initiate late onset Alzheimer disease (LOAD): towards a new paradigm.Semantic proximity Read ↗

SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians.Semantic proximity Read ↗

Bridging integrator 1 (BIN1): form, function, and Alzheimer's disease.Semantic proximity Read ↗

Pin1 contribution to Alzheimer's disease: transcriptional and epigenetic mechanisms in patients with late-onset Alzheimer's disease.Semantic proximity Read ↗

Role of the Transforming-Growth-Factor-β1 Gene in Late-Onset Alzheimer’s Disease: Implications for the TreatmentSemantic proximity Read ↗

Association between methylation of BIN1 promoter in peripheral blood and preclinical Alzheimer’s diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.