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Article

Do epigenetic pathways initiate late onset Alzheimer disease (LOAD): towards a new paradigm.

Current Alzheimer research - 1 Jun 2012

Bihaqi Syed Waseem, Schumacher Axel, Maloney Bryan, Lahiri Debomoy K, Zawia Nasser H

Abstract excerpt

Late onset Alzheimer's disease (LOAD) is a non-familial, progressive neurodegenerative disease and the most prominent form of dementia in the elderly. Accumulating evidence suggests that LOAD not only results from the combined effects of variation in a number of genes and environmental factors, but also from epigenetic abnormalities such as histone modifications or DNA methylation. In comparison to monogenic...

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PMID: 22300405
DOI: 10.2174/156720512800617982

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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