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Article

Distinct Cell Surface Expression Patterns of N-Glycosylation Site Mutants of AMPA-Type Glutamate Receptor under the Homo-Oligomeric Expression Conditions.

International journal of molecular sciences - 19 Jul 2020

Morise Jyoji, Yamamoto Saki, Midorikawa Ryosuke, Takamiya Kogo, Nonaka Motohiro, Takematsu Hiromu, Oka Shogo

Abstract excerpt

The AMPA-type glutamate receptor (AMPAR) is a homotetrameric or heterotetrameric ion channel composed of various combinations of four subunits (GluA1-4), and its abundance in the synapse determines the strength of synaptic activity. The formation of oligomers in the endoplasmatic reticulum (ER) is crucial for AMPAR subunits' ER-exit and translocation to the cell membrane. Although N-glycosylation on different...

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Identifiers

PMID: 32707739
DOI: 10.3390/ijms21145101
PMCID: PMC7404163

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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