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Article

N-glycosylation of the AMPA-type glutamate receptor regulates cell surface expression and tetramer formation affecting channel function.

Journal of neurochemistry - 1 Dec 2018

Kandel Munal Babu, Yamamoto Saki, Midorikawa Ryosuke, Morise Jyoji, Wakazono Yoshihiko, Oka Shogo, Takamiya Kogo

Abstract excerpt

The AMPA-type glutamate receptor (AMPA-R) plays a primary role in principal excitatory synaptic transmission and many neuronal functions including synaptic plasticity that underlie learning and memory. N-glycosylation is one of the major post-translational modifications of membrane proteins, but its specific roles in neurons remain largely unknown. AMPA-R subunits are N-glycosylated at their extracellular domains...

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Identifiers

PMID: 30092607
DOI: 10.1111/jnc.14565

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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