Article
Development of DNA controls for detection of β-thalassemia mutations commonly found in Asian.
International journal of laboratory hematology - 1 Dec 2020
Munkongdee Thongperm, Nualkaew Tiwaporn, Buasuwan Nattrika, Hinna Nurmeeha, Paiboonsukwong Kittiphong, Sripichai Orapan, Svasti Saovaros, Winichagoon Pranee, Fucharoen Suthat, Jearawiriyapaisarn Natee
Abstract excerpt
INTRODUCTION: Several DNA-based approaches including a reverse dot-blot hybridization (RDB) have been established for detection of β-thalassemia genotypes to provide accurate genetic counseling and prenatal diagnosis for prevention and control of severe β-thalassemia. However, one of major concerns of these techniques is a risk of misdiagnosis due to a lack of DNA controls. Here, we constructed positive DNA...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.