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Development and evaluation of a reverse dot blot assay for the simultaneous detection of common alpha and beta thalassemia in Chinese.

Blood cells, molecules & diseases - 15 Feb 2012

Lin Min, Zhu Juan-Juan, Wang Qian, Xie Long-Xu, Lu Min, Wang Jun-Li, Wang Chun-Fang, Zhong Tian-Yu, Zheng Lei, Pan Mei-Chen, Wu Jiao-Ren, Wen Ying-Fang, Liu Gui-Rong, Zhan Xiao-Fen, Lin Fen, Yang Li-Ye

Abstract excerpt

Thalassemia is the commonest inherited autosomal recessive disorders of hemoglobin in southern China. We developed and evaluated a reverse dot blot (RDB) assay combined with flow-through hybridization technology platform for the rapid and simultaneous identification of 5 types of α-thalassemia and 16 types of β-thalassemia common in Chinese. Reliable genotyping of wild-type and thalassemic genomic DNA samples was...

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PMID: 22197394
DOI: 10.1016/j.bcmd.2011.12.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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