Article
[Rapid prenatal diagnosis of 60 cases with beta-thalassemia by reverse dot blot analysis].
Zhonghua fu chan ke za zhi - 1 Jun 1996
Liao C, Xu X, Huang Y
Abstract excerpt
OBJECTIVE: To evaluate the rapid prenatal diagnosis method for beta-thalassemia by reverse dot blot (RDB) analysis. METHODS: Using RDB analysis which can detect 18 types of beta-thalassemia mutation, 60 fetuses (with 1 twin) suspected of beta-thalassemia from 59 couples in Southern China were investigated. RESULTS: 15 fetus had normal genotype, 34 were carriers of heterozygous with one of parental affected gene;...
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