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Article

UBASH3A deficiency accelerates type 1 diabetes development and enhances salivary gland inflammation in NOD mice.

Scientific reports - 21 Jul 2020

Chen Yi-Guang, Ciecko Ashley E, Khaja Shamim, Grzybowski Michael, Geurts Aron M, Lieberman Scott M

Abstract excerpt

Recent advances in genetic analyses have significantly refined human type 1 diabetes (T1D) associated loci. The goal of such effort is to identify the causal genes and have a complete understanding of the molecular pathways that independently or interactively influence cellular processes leading to the destruction of insulin producing pancreatic β cells. UBASH3A has been suggested as the underlying gene for a...

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Source

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Identifiers

PMID: 32694640
DOI: 10.1038/s41598-020-68956-6
PMCID: PMC7374577

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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