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Article

Fibrinogen and magnesium combination biomaterials modulate macrophage phenotype, NF-kB signaling and crosstalk with mesenchymal stem/stromal cells.

Acta biomaterialia - 15 Sept 2020

Bessa-Gonçalves Mafalda, Silva Andreia M, Brás João P, Helmholz Heike, Luthringer-Feyerabend Bérengère J C, Willumeit-Römer Regine, Barbosa Mário A, Santos Susana G

Abstract excerpt

Macrophage behavior upon biomaterial implantation conditions the inflammatory response and subsequent tissue repair. The hypothesis behind this work was that fibrinogen (Fg) and magnesium (Mg) biomaterials, used in combination (FgMg) could act synergistically to modulate macrophage activation, promoting a pro-regenerative phenotype. Materials were characterized by scanning electron microscopy, Fg and Mg...

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Identifiers

PMID: 32688091
DOI: 10.1016/j.actbio.2020.07.028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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