Article
Five genetic polymorphisms of cytochrome P450 enzymes in the Czech non-Roma and Czech Roma population samples.
Drug metabolism and personalized therapy - 30 Jun 2020
Dlouhá Lucie, Adámková Věra, Šedová Lenka, Olišarová Věra, Hubáček Jaroslav A, Tóthová Valérie
Abstract excerpt
Objectives Cytochromes P450 play a role in human drugs metabolic pathways and their genes are among the most variable in humans. The aim of this study was to analyze genotype frequencies of five common polymorphisms of cytochromes P450 in Roma/Gypsy and Czech (non-Roma) population samples with Czech origin. Methods Roma/Gypsy (n=302) and Czech subjects (n=298) were genotyped for CYP1A2 (rs762551), CYP2A6...
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