Article
Genetic Polymorphisms of Cytochrome P450 Enzymes and Transport Proteins in a Russian Population and Three Ethnic Groups of Dagestan.
Genetic testing and molecular biomarkers - 1 Dec 2017
Mirzaev Karin B, Sychev Dmitry A, Ryzhikova Kristina A, Konova Olga D, Mammaev Suleiman N, Gafurov Daniyal M, Shuev Grigorij N, Grishina Elena A, Sozaeva Zhannet A
Abstract excerpt
AIM: The objective of this study was to investigate the prevalence of polymorphic markers of the CYP2C19, CYP2C9, CYP2D6, SLCO1B1, and ABCB1 genes among the three ethnic groups in Dagestan and compare it with the carrier frequency of these markers among the Russian population living in Moscow. METHODS: The study involved 186 healthy, unrelated, and chronic medication-free volunteers (53 males and 133 females) of...
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