Article
PfMAP-2 is essential for male gametogenesis in the malaria parasite Plasmodium falciparum.
Scientific reports - 17 Jul 2020
Hitz Eva, Balestra Aurélia C, Brochet Mathieu, Voss Till S
Abstract excerpt
In malaria parasites, male gametogenesis is a proliferative stage essential for parasite transmission to the mosquito vector. It is a rapid process involving three rounds of genome replication alternating with closed endomitoses, and assembly of axonemes to produce eight flagellated motile microgametes. Studies in Plasmodium berghei have highlighted tight regulation of gametogenesis by a network of kinases. The...
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