Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional characterization of both MAP kinases of the human malaria parasite Plasmodium falciparum by reverse genetics.

Molecular microbiology - 1 Sept 2007

Dorin-Semblat Dominique, Quashie Neils, Halbert Jean, Sicard Audrey, Doerig Caroline, Peat Elizabeth, Ranford-Cartwright Lisa, Doerig Christian

Abstract excerpt

The kinome of the human malaria parasite Plasmodium falciparum includes two genes encoding mitogen-activated protein kinase (MAPK) homologues, pfmap-1 and pfmap-2, but no clear orthologue of the MAPK kinase (MAPKK) family, raising the question of the mode of activation and function of the plasmodial MAPKs. Functional studies in the rodent malaria model Plasmodium berghei recently showed the map-2 gene to be...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anopheles
Share to Erythrocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Isoenzymes

Share to Malaria, Falciparum

Share to Mitogen-Activated Protein Kinases

Share to Phenotype

Share to Plasmodium falciparum

Share to Protozoan Proteins

Source

Identifiers

PMID: 17651389
DOI: 10.1111/j.1365-2958.2007.05859.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional characterization of both MAP kinases of the human malaria parasite Plasmodium falciparum by reverse genetics.PMID 17651389Read ↗

PfMAP-2 is essential for male gametogenesis in the malaria parasite Plasmodium falciparum.Semantic proximity Read ↗

The systematic functional analysis of Plasmodium protein kinases identifies essential regulators of mosquito transmission.Semantic proximity Read ↗

Protein kinases of the human malaria parasite Plasmodium falciparum: the kinome of a divergent eukaryote.Semantic proximity Read ↗

Identification of Three Novel Plasmodium Factors Involved in Ookinete to Oocyst Developmental TransitionSemantic proximity Read ↗

Epistasis studies reveal redundancy among calcium-dependent protein kinases in motility and invasion of malaria parasitesSemantic proximity Read ↗

Sexual Development in Plasmodium: Lessons from Functional AnalysesSemantic proximity Read ↗

Studies on the kinome of Plasmodium falciparum and biochemical characterization of atypical protein kinasesSemantic proximity Read ↗

Inducible developmental reprogramming redefines commitment to sexual development in the malaria parasite Plasmodium bergheiSemantic proximity Read ↗

Plasmodium falciparum Calcium-Dependent Protein Kinase 2 Is Critical for Male Gametocyte Exflagellation but Not Essential for Asexual ProliferationSemantic proximity Read ↗

A MAP kinase homologue from the human malaria parasite, Plasmodium falciparumSemantic proximity Read ↗

A Unique Protein Phosphatase with Kelch-Like Domains (PPKL) in Plasmodium Modulates Ookinete Differentiation, Motility and InvasionSemantic proximity Read ↗

Epigenomics and gametocytogenesis in the rodent malaria model, Plasmodium bergheiSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.