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Article

An essential role for the Plasmodium Nek-2 Nima-related protein kinase in the sexual development of malaria parasites.

The Journal of biological chemistry - 31 Jul 2009

Reininger Luc, Tewari Rita, Fennell Clare, Holland Zoe, Goldring Dean, Ranford-Cartwright Lisa, Billker Oliver, Doerig Christian

Abstract excerpt

The molecular control of cell division and development in malaria parasites is far from understood. We previously showed that a Plasmodium gametocyte-specific NIMA-related protein kinase, nek-4, is required for completion of meiosis in the ookinete, the motile form that develops from the zygote in the mosquito vector. Here, we show that another NIMA-related kinase, Pfnek-2, is also predominantly expressed in...

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Identifiers

PMID: 19491095
DOI: 10.1074/jbc.M109.017988
PMCID: PMC2742851

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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