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An essential role of the basal body protein SAS ‐6 in P lasmodium male gamete development and malaria transmission

26 Aug 2014

Abstract excerpt

Gametocytes are the sole Plasmodium parasite stages that infect mosquitoes; therefore development of functional gametes is required for malaria transmission. Flagellum assembly of the Plasmodium male gamete differs from that of most other eukaryotes in that it is intracytoplasmic but retains a key conserved feature: axonemes assemble from basal bodies. The centriole/basal body protein SAS-6 normally regulates...

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PMID: 25154861
DOI: 10.1111/cmi.12355

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