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Dissecting the role of PfAP2-G in malaria gametocytogenesis

20 Mar 2020

Abstract excerpt

In the malaria parasite Plasmodium falciparum, the switch from asexual multiplication to sexual differentiation into gametocytes is essential for transmission to mosquitos. The transcription factor PfAP2-G is a key determinant of sexual commitment that orchestrates this crucial cell fate decision. Here we identify the direct targets of PfAP2-G and demonstrate that it dynamically binds hundreds of sites across the...

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PMID: 32198457
DOI: 10.1038/s41467-020-15026-0

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Dissecting the role of PfAP2-G in malaria gametocytogenesisPMID 32198457Read ↗

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